Docking based 3D-QSAR studies applied at the BRAF inhibitors to understand the binding mechanism
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چکیده
منابع مشابه
Docking based 3D-QSAR studies applied at the BRAF inhibitors to understand the binding mechanism
B-RaF is a member of the RAF family of serine/threonine kinases involved in the regulation of cell growth, differentiation, and proliferation. It forms part of a conserved apoptosis signals through the RAS-RAF-MAPK pathway. As an important target of the cancer treatment B-Raf has more potential for researcher. The discovery of the B-RAF mutation [1] has elevated expectation for targeted therapy...
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ژورنال
عنوان ژورنال: Journal of Cheminformatics
سال: 2012
ISSN: 1758-2946
DOI: 10.1186/1758-2946-4-s1-p46